BDBM50102145 1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-2-oxo-ethyl}-2-(4-fluoro-benzylsulfanyl)-5-pyrimidin-5-ylmethyl-1H-pyrimidin-4-one::CHEMBL299694

SMILES Fc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2CC(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)cc1

InChI Key InChIKey=CVDWKFWJHPDNLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102145   

TargetPlatelet-activating factor acetylhydrolase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50102145(1-{2-[4-(4-Chloro-benzyl)-piperazin-1-yl]-2-oxo-et...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human lipoprotein associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed