BDBM50103025 (S)-5-Guanidino-2-[(S)-2-{3-[1-(2-methyl-benzyl)-3-pyrrolidin-1-ylmethyl-1H-indol-6-yl]-ureido}-3-(4-nitro-phenyl)-propionylamino]-pentanoic acid benzylamide::CHEMBL265227

SMILES Cc1ccccc1Cn1cc(CN2CCCC2)c2ccc(NC(=O)NC(Cc3ccc(cc3)[N+]([O-])=O)C(=O)NC(CCC[N-]C(N)=[NH2+])C(=O)NCc3ccccc3)cc12

InChI Key InChIKey=IACDZAFLXXSMDB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103025   

TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103025((S)-5-Guanidino-2-[(S)-2-{3-[1-(2-methyl-benzyl)-3...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103025((S)-5-Guanidino-2-[(S)-2-{3-[1-(2-methyl-benzyl)-3...)
Affinity DataIC50: 800nMAssay Description:In vitro displacement of [3H]S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 uM) from thrombin receptor (PAR-1) on the membranes of CHRF-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103025((S)-5-Guanidino-2-[(S)-2-{3-[1-(2-methyl-benzyl)-3...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed