BDBM50103133 1-[(R)-2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol::CHEMBL70918

SMILES Cc1ccc(CC2(O)CCN(C[C@H](O)Cc3ccc(O)cc3)CC2)cc1

InChI Key InChIKey=MAQRRFANFOCRSD-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103133   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50103133(1-[(R)-2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4...)
Affinity DataIC50: 19nMAssay Description:Evaluated for in vitro inhibition of recombinant rat NR1C/2B receptor expressed in xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50103133(1-[(R)-2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4...)
Affinity DataKi:  7.30E+3nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]prazosin radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50103133(1-[(R)-2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for in vitro inhibition of recombinant rat NR1C/2A receptor expressed in xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed