BDBM50103177 CHEMBL307079::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethyl-benzamide

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(C)cc1C(=O)NO

InChI Key InChIKey=CBLOGBROLDHLEE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103177   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103177(N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3...)
Affinity DataIC50: 11nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103177(N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3...)
Affinity DataIC50: 15nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50103177(N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103177(N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3...)
Affinity DataIC50: 132nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed