BDBM50103417 1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL319458

SMILES CCCCCC1(CCCCC)NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1

InChI Key InChIKey=DGSMSHNIDMODOQ-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50103417   

TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataIC50: 0.840nMAssay Description:Inhibitory concentration required to inhibit SRIF-14 induced reduction of cAMP in CHO-K1 cells expressing the human sst3 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-2) subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-5) subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50103417(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-1) subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed