BDBM50103999 CHEMBL105279::N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(3-methoxy-benzylsulfanyl)-butyramide

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)C(CCSCc1cccc(OC)c1)C(=O)NO

InChI Key InChIKey=ACXYSVKNGLLDLY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50103999   

TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103999(N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103999(N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 3.80nMAssay Description:In vitro inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103999(N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 5.30nMAssay Description:In vitro inhibition of human matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103999(N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 5.70nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103999(N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 297nMAssay Description:In vitro inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed