BDBM50104251 Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid benzyl ester::CHEMBL82168

SMILES CN(C[C@@H](CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccccc1)c1ccccc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=KBSWOGHNRPKEDN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50104251   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104251(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-p...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104251(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-p...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at Homo sapiens (human) CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104251(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed