BDBM50104275 CHEMBL79622::{1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-propyl-carbamic acid 4-carbamoyl-benzyl ester

SMILES CCCN(C1CCN(CC[C@H](CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1)C(=O)OCc1ccc(cc1)C(N)=O

InChI Key InChIKey=OKAYRNKUARTJKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104275   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104275({1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104275({1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at Homo sapiens (human) CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article