BDBM50104506 3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2-yl]-meth-(Z)-ylidene]-6-[1-p-tolyl-meth-(Z)-ylidene]-piperazine-2,5-dione::CHEMBL314374

SMILES Cc1ccc(/C=c2\[nH]c(=O)/c(=C/c3ccc(SCCN(C)C)s3)[nH]c2=O)cc1

InChI Key InChIKey=VXGFQHWMLSKINS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104506   

TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104506BDBM50104506(3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2...)
Affinity DataIC50: 1.24E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed