BDBM50104545 2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-1-(3aR,7aS)-octahydro-isoindol-2-yl-propan-1-one::CHEMBL86431

SMILES C[C@H](CNCCCCc1ccncc1)c1c([nH]c2ccc(cc12)C(C)(C)C(=O)N1C[C@H]2CCCC[C@H]2C1)-c1cc(C)cc(C)c1

InChI Key InChIKey=GVCFXLOSGDFPGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104545   

TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104545(2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-py...)
Affinity DataIC50: 1.40nMAssay Description:Binding inhibition towards human pituitary gonadotropin-releasing hormone receptor using [125I]buserelin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104545(2-{2-(3,5-Dimethyl-phenyl)-3-[(S)-1-methyl-2-(4-py...)
Affinity DataIC50: 66nMAssay Description:In vitro functional antagonism via inhibition of GnRH-stimulated phosphatidylinositol (PI) hydrolysis in cloned Chinese hamster ovary (CHO) cells sta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed