BDBM50104860 CHEMBL113620::N-(2,2-Dimethyl-3-phenyl-cyclopropanecarbonyl)-guanidine

SMILES CC1(C)[C@@H]([C@H]1c1ccccc1)C(=O)NC(N)=N

InChI Key InChIKey=IFAKNPAXQPARQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104860   

TargetSodium/hydrogen exchanger 1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50104860(N-(2,2-Dimethyl-3-phenyl-cyclopropanecarbonyl)-gua...)
Affinity DataIC50: 69nMAssay Description:Inhibition of NHE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50104860(N-(2,2-Dimethyl-3-phenyl-cyclopropanecarbonyl)-gua...)
Affinity DataIC50: 69nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed