BDBM50104971 CHEMBL115712::N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobutyl-succinamide

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H]1[C@@H](O)Cc2ccccc12

InChI Key InChIKey=ZYIMYAJZHPOFQU-IVMMDQJWSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104971   

TargetNeutrophil collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104971(CHEMBL115712 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  303nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104971(CHEMBL115712 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104971(CHEMBL115712 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104971(CHEMBL115712 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed