BDBM50105021 4-tert-Butyl-N-{5-(4-isopropyl-phenyl)-6-[2-(5-methylsulfanyl-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-yl}-benzenesulfonamide::CHEMBL115230

SMILES CSc1cnc(OCCOc2ncnc(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)c2-c2ccc(cc2)C(C)C)nc1

InChI Key InChIKey=TWWWIUXRXGITJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105021   

TargetEndothelin-1 receptor(Pig)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105021(4-tert-Butyl-N-{5-(4-isopropyl-phenyl)-6-[2-(5-met...)
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibition of [125I]ET1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed