BDBM50105111 1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperidin-4-yl]-1,4-dihydro-quinoxaline-2,3-dione::CHEMBL325945

SMILES Clc1cc2OCOc2cc1CN1CCC(CC1)n1c2ccccc2[nH]c(=O)c1=O

InChI Key InChIKey=VPZVRDLFBIYDOY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50105111   

TargetDelta-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105111(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  620nMAssay Description:Inhibition of ligand binding to human delta opioid receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105111(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  6.55E+3nMAssay Description:Inhibition of human dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105111(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  434nMAssay Description:Inhibition of human ORL1 orphanin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105111(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  6.30nMAssay Description:Binding affinity against mu opiate receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105111(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  32nMAssay Description:Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105111(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  1.52E+3nMAssay Description:Binding affinity against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed