BDBM50105235 2-Methyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,8-dioxa-1lambda*6*-thia-2-aza-anthracene-3-carboxylic acid (5-benzenesulfonylamino-1-formyl-pentyl)-amide::CHEMBL333622

SMILES CN1C(Cc2cc3OCCOc3cc2S1(=O)=O)C(=O)N[C@@H](CCCCNS(=O)(=O)c1ccccc1)C=O

InChI Key InChIKey=LHNMAPVBKWRJSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105235   

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105235(2-Methyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,8-dioxa...)
Affinity DataIC50: 36nMAssay Description:Inhibitory activity towards human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105235(2-Methyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,8-dioxa...)
Affinity DataIC50: 107nMAssay Description:Inhibitory activity towards human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105235(2-Methyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,8-dioxa...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against MOLT-4 cells (human T-cell leukemia cell line)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed