BDBM50105250 2-Methyl-1-oxo-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1-benzyl-2-oxo-ethyl)-amide::CHEMBL326758

SMILES CN1C(Cc2ccccc2C1=O)C(=O)N[C@@H](Cc1ccccc1)C=O

InChI Key InChIKey=CAPXGUVOBVIJQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105250   

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105250(2-Methyl-1-oxo-1,2,3,4-tetrahydro-isoquinoline-3-c...)
Affinity DataIC50: 85nMAssay Description:Compound was evaluated for inhibitory activity towards human calpain I isomer 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed