BDBM50105563 1-Benzyl-6-(3-chloro-phenyl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL92026

SMILES O=c1[nH]c2ccc(-c3cccc(Cl)c3)cc2n1Cc1ccccc1

InChI Key InChIKey=HMLVMHDKNACECO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105563   

TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105563BDBM50105563(1-Benzyl-6-(3-chloro-phenyl)-1,3-dihydro-benzoimid...)
Affinity DataIC50: 113nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105563BDBM50105563(1-Benzyl-6-(3-chloro-phenyl)-1,3-dihydro-benzoimid...)
Affinity DataIC50: 412nMAssay Description:Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105563BDBM50105563(1-Benzyl-6-(3-chloro-phenyl)-1,3-dihydro-benzoimid...)
Affinity DataKi:  521nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed