BDBM50105617 3-[3-(1-Benzyl-1H-pyrazol-3-yl)-ureido]-5-tert-butyl-thiophene-2-carboxylic acid methyl ester::CHEMBL317109

SMILES COC(=O)c1sc(cc1NC(=O)Nc1ccn(Cc2ccccc2)n1)C(C)(C)C

InChI Key InChIKey=ZLBZPXISWSFBTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105617   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105617(3-[3-(1-Benzyl-1H-pyrazol-3-yl)-ureido]-5-tert-but...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed