BDBM50105831 CHEMBL3597584
SMILES [O-][N+](=O)c1cccnc1N1CCN(CC1)C(=O)C#Cc1ccccc1
InChI Key InChIKey=GBLQNGDWYYUAAX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50105831
TargetMetabotropic glutamate receptor 5(Human)
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]MPEP from human cloned mGluR5 receptor expressed in CHO-T-Rex cells after 60 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]MPEP from mGluR5 receptor in Sprague-Dawley rat forebrain membrane after 60 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 97nMAssay Description:Displacement of [3H]R214127 from rat cloned mGluR1 receptor expressed in CHO-T-Rex cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 271nMAssay Description:Negative allosteric modulatory activity at rat cloned mGluR1 receptor expressed in CHO-T-Rex cells assessed as inhibiton of quisqualate-induced calci...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Human)
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Negative allosteric modulatory activity at human cloned mGluR5 receptor expressed in CHO-T-Rex cells assessed as inhibiton of quisqualate-induced cal...More data for this Ligand-Target Pair