BDBM50106114 (2-Bromo-phenyl)-[1-(3H-imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-methanone::CHEMBL317408

SMILES Brc1ccccc1C(=O)c1cn(Cc2cnc[nH]2)cc1-c1cccc2ccccc12

InChI Key InChIKey=MVAGGJAVZTXHOY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106114   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Lgci

Curated by ChEMBL

LigandBDBM50106114((2-Bromo-phenyl)-[1-(3H-imidazol-4-ylmethyl)-4-nap...)Copy SMILESCopy InChI

Affinity DataIC50: 88nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-ras protein by FarnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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