BDBM50106666 3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cyclohexylmethyl)-pentanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL339381

SMILES CC(C)[C@@H]([C@@H](CC1CCC(C)CC1)C(=O)N[C@@H](CCCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1)N(O)C=O

InChI Key InChIKey=ZAUSLRXPYLUTHB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106666   

LigandPNGBDBM50106666(3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cycl...)
Affinity DataIC50: 14nMAssay Description:Inhibition of TACE using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106666(3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cycl...)
Affinity DataIC50: 89nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106666(3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cycl...)
Affinity DataIC50: 122nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106666(3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cycl...)
Affinity DataIC50: 155nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed