BDBM50106668 (2R,3R)-N-{(1R)-4-Nitroguanyl-2-[((2R)-2-{(1S)-1-[formyl(hydroxy)amino]ethyl}-4-methylpentanoyl)amino]-3-methyl-N-1,3-thiazol-2-yl)pentanamide::CHEMBL135590

SMILES CC(C)C[C@H]([C@H](C)N(O)C=O)C(=O)N[C@@H]([C@H](C)CCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1

InChI Key InChIKey=HUBNMJYLBBXLHV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106668   

LigandPNGBDBM50106668((2R,3R)-N-{(1R)-4-Nitroguanyl-2-[((2R)-2-{(1S)-1-[...)
Affinity DataIC50: 7nMAssay Description:Inhibition of TACE using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106668((2R,3R)-N-{(1R)-4-Nitroguanyl-2-[((2R)-2-{(1S)-1-[...)
Affinity DataIC50: 19nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106668((2R,3R)-N-{(1R)-4-Nitroguanyl-2-[((2R)-2-{(1S)-1-[...)
Affinity DataIC50: 38nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106668((2R,3R)-N-{(1R)-4-Nitroguanyl-2-[((2R)-2-{(1S)-1-[...)
Affinity DataIC50: 273nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed