BDBM50107108 (1S,2S,3R)-2-(Amino-carboxy-methyl)-3-[2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid::CHEMBL325140

SMILES NC([C@H]1[C@@H](CCC2c3ccccc3Oc3ccccc23)[C@@H]1C(O)=O)C(O)=O

InChI Key InChIKey=MBCWMEYAVJTLQS-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107108   

TargetMetabotropic glutamate receptor 3(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50107108((1S,2S,3R)-2-(Amino-carboxy-methyl)-3-[2-(9H-xanth...)
Affinity DataIC50: 75nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]glutamate against rat recombinant Metabotropic glutamate receptor 3 expressed in HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50107108((1S,2S,3R)-2-(Amino-carboxy-methyl)-3-[2-(9H-xanth...)
Affinity DataKi:  85nMAssay Description:Antagonistic activity against stimulation of GTP (gamma) 35 S binding by glutamate in membranes from CHO cells expressing human Metabotropic glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50107108((1S,2S,3R)-2-(Amino-carboxy-methyl)-3-[2-(9H-xanth...)
Affinity DataIC50: 200nMAssay Description:Antagonistic activity against stimulation of GTP (gamma) 35 S binding by glutamate in membranes from CHO cells expressing human Metabotropic glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed