BDBM50107240 CHEMBL344432::[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-[2-(pyridin-2-yloxy)-ethyl]-amine

SMILES COc1cccc2C(CCCNCCOc3ccccn3)CCCc12

InChI Key InChIKey=HETKYUVAGHVYTA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50107240   

Target5-hydroxytryptamine receptor 1A(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50107240([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity on human cloned 5-hydroxytryptamine 1A receptor transfected in human cell lines(He La)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50107240([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi:  0.540nMAssay Description:Binding was determined on 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50107240([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi:  0.550nMAssay Description:Binding affinity was determined on human cloned Alpha-1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50107240([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi:  12.7nMAssay Description:Binding affinity towarda alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50107240([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi:  26.4nMAssay Description:Binding affinity was determined on human cloned alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50107240([3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-...)
Affinity DataKi: >850nMAssay Description:Binding affinity towards dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed