BDBM50107501 CHEMBL155227::N-(4'-Chloro-biphenyl-4-ylmethyl)-2-[5-(1-ethyl-2-oxo-1,2-dihydro-pyrimidin-5-ylmethyl)-2-(4-fluoro-benzylsulfanyl)-4-oxo-4H-pyrimidin-1-yl]-N-methyl-acetamide

SMILES CCn1cc(Cc2cn(CC(=O)N(C)Cc3ccc(cc3)-c3ccc(Cl)cc3)c(SCc3ccc(F)cc3)nc2=O)cnc1=O

InChI Key InChIKey=MAALXUIAYAMCIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107501   

TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107501(CHEMBL155227 | N-(4'-Chloro-biphenyl-4-ylmethyl)-2...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2 (Lp-PLA2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed