BDBM50107504 CHEMBL154817::N-(4'-Chloro-biphenyl-4-ylmethyl)-4-[2-(4-fluoro-benzylsulfanyl)-5-(2-methoxy-pyrimidin-5-ylmethyl)-4-oxo-4H-pyrimidin-1-yl]-butyramide

SMILES COc1ncc(Cc2cn(CCCC(=O)NCc3ccc(cc3)-c3ccc(Cl)cc3)c(SCc3ccc(F)cc3)nc2=O)cn1

InChI Key InChIKey=HMXGSDCSSJMFAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107504   

TargetPlatelet-activating factor acetylhydrolase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107504(N-(4'-Chloro-biphenyl-4-ylmethyl)-4-[2-(4-fluoro-b...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2 (Lp-PLA2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed