BDBM50107528 4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benzenesulfonamide::CHEMBL290192

SMILES Cc1nc(c(o1)-c1ccc(cc1)S(N)(=O)=O)-c1ccc(F)cc1

InChI Key InChIKey=HYEBIIAQOZKAGA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107528   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50:  4.70E+3nMAssay Description:In vitro inhibitory activity of the compound towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory activity of the compound towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed