BDBM50108141 CHEMBL76757::N-[1-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-ylmethyl)-2-(4'-methylsulfanyl-biphenyl-4-sulfonyl)-ethyl]-N-hydroxy-formamide

SMILES CSc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)CC(CN1C(=O)NC(C)(C)C1=O)N(O)C=O

InChI Key InChIKey=MMRISAVXAFHOJP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108141   

Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108141(N-[1-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-ylmeth...)
Affinity DataIC50: 0.670nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108141(N-[1-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-ylmeth...)
Affinity DataIC50: 1.10nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108141(N-[1-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-ylmeth...)
Affinity DataIC50: 2.90nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed