BDBM50108291 CHEMBL36891::Indolocarbazole analogue
SMILES CCSCc1ccc2n3[C@H]4C[C@](O)(C(=O)OC)[C@](C)(O4)n4c5ccccc5c5c6CNC(=O)c6c(c2c1)c3c45
InChI Key InChIKey=LYFDGRJCBMWOKJ-YCIRJXQPSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50108291
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of NGF high affinity receptor tyrosine kinase TrkAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
TargetProtein kinase C alpha/beta/delta/epsilon/eta/gamma/theta/zeta type(Rattus norvegicus)
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 222nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair