BDBM50108346 CHEMBL295295::Indole Derivative

SMILES C[C@H]1c2c([nH]c3ccccc23)[C@@H]2Oc3c(O)ccc4c3C23CCN(C)C(C4)C13

InChI Key InChIKey=BKKGVUYVPORNKS-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50108346   

TargetDelta-type opioid receptor(Rat)
Niddk

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108346BDBM50108346(Indole Derivative | CHEMBL295295)
Affinity DataKi:  0.700nMAssay Description:Binding affinity for delta opioid receptor by displacing [3H]DADL was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108346BDBM50108346(Indole Derivative | CHEMBL295295)
Affinity DataKi:  49nMAssay Description:Binding affinity for gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Niddk

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108346BDBM50108346(Indole Derivative | CHEMBL295295)
Affinity DataKi:  126nMAssay Description:Binding affinity for kappa opioid receptor by displacing [3H]U-69593 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Niddk

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108346BDBM50108346(Indole Derivative | CHEMBL295295)
Affinity DataKi:  240nMAssay Description:Binding affinity for mu opioid receptor by displacing [3H]-DAMGO was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Niddk

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108346BDBM50108346(Indole Derivative | CHEMBL295295)
Affinity DataKi:  398nMAssay Description:Binding affinity for kappa opioid receptor by displacing U-69,593 was determined in [35S]GTP gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Niddk

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108346BDBM50108346(Indole Derivative | CHEMBL295295)
Affinity DataKi: >600nMAssay Description:Binding affinity for mu opioid receptor by displacing DAMGO was determined in [35S]-GTP gamma-S binding assay; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed