BDBM50108446 3-(4-Methoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one::CHEMBL305552

SMILES COc1ccc(cc1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O

InChI Key InChIKey=FFTCTZCOJYMKCU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108446   

TargetKappa-type opioid receptor(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108446(3-(4-Methoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl...)
Affinity DataIC50: 49nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108446(3-(4-Methoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl...)
Affinity DataIC50: 1.46E+3nMAssay Description:Binding affinity towards mu opioid receptor by the displacement of [125I]EnkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108446(3-(4-Methoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl...)
Affinity DataIC50: 5.21E+3nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [125I]-DeltorphinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed