BDBM50108594 (+/-)2-[4-(7-Bromo-9,10-dihydro-4-thia-10a-aza-benzo[f]azulen-9-yl)-piperazin-1-yl]-ethanol::CHEMBL116542

SMILES OCCN1CCN(CC1)C1Cn2cccc2Sc2ccc(Br)cc12

InChI Key InChIKey=ZAYWFUSENFQTME-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108594   

TargetD(2) dopamine receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50108594((+/-)2-[4-(7-Bromo-9,10-dihydro-4-thia-10a-aza-ben...)
Affinity DataKi:  5nMAssay Description:Half-maximal inhibition of [3H]spiperone binding to Dopamine receptor D2 in rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50108594((+/-)2-[4-(7-Bromo-9,10-dihydro-4-thia-10a-aza-ben...)
Affinity DataKi:  10nMAssay Description:Half-maximal inhibition of [3H]-7-OH-DPAT binding to Dopamine receptor D3 in rat tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50108594((+/-)2-[4-(7-Bromo-9,10-dihydro-4-thia-10a-aza-ben...)
Affinity DataKi:  20nMAssay Description:Half-maximal inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50108594((+/-)2-[4-(7-Bromo-9,10-dihydro-4-thia-10a-aza-ben...)
Affinity DataKi:  23nMAssay Description:Half-maximal inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed