BDBM50108624 CHEMBL3597966

SMILES O=C(c1ccccc1-c1cccs1)N1C2CCC1[C@H](COc1ccc(F)cn1)C2

InChI Key InChIKey=JIEFEDOEWSOKJT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108624   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108624BDBM50108624(CHEMBL3597966)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human orexin-1 receptor expressed in CFiQ cells assessed as inhibition of orexin-A-induced Ca2+ release preincubated for 15 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108624BDBM50108624(CHEMBL3597966)
Affinity DataKi:  12nMAssay Description:Antagonist activity at human orexin-2 receptor expressed in human PFSK-1 cells assessed as inhibition of orexin-B-induced Ca2+ release preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed