BDBM50108752 1-{4-[4-(4,6-Diisopropyl-pyrimidin-2-yl)-piperazin-1-yl]-pyrimidin-2-yl}-ethanol::CHEMBL150734

SMILES CC(C)c1cc(nc(n1)N1CCN(CC1)c1ccnc(n1)[C@@H](C)O)C(C)C

InChI Key InChIKey=TVDLCASQGHHNHG-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108752   

TargetSorbitol dehydrogenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108752(1-{4-[4-(4,6-Diisopropyl-pyrimidin-2-yl)-piperazin...)
Affinity DataIC50:  72nMAssay Description:Concentration required for 50% in vitro inhibition of recombinant human sorbitol dehydrogenase (h-SDH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed