BDBM50109272 CHEMBL3601533

SMILES NS(=O)(=O)Oc1ccc(NC(=O)N2CCN(CC2)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=FHBNALWMHNMNKL-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50109272   

TargetCarbonic anhydrase 9(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109272(CHEMBL3601533)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant carbonic anhydrase-9 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109272(CHEMBL3601533)
Affinity DataKi:  17nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109272(CHEMBL3601533)
Affinity DataKi:  85nMAssay Description:Inhibition of human recombinant carbonic anhydrase-12 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109272(CHEMBL3601533)
Affinity DataIC50: 94nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cell using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109272(CHEMBL3601533)
Affinity DataKi:  581nMAssay Description:Inhibition of human recombinant carbonic anhydrase-1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50109272(CHEMBL3601533)
Affinity DataKi:  2.59E+6nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed