BDBM50109322 CHEMBL114761::[4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-(2-methyl-propenyl)-pyridin-3-yl]-methanol

SMILES [#6]-[#6](-[#6])-c1nc(-[#6](-[#6])-[#6])c(\[#6]=[#6](\[#6])-[#6])c(-c2ccc(F)cc2)c1-[#6]-[#8]

InChI Key InChIKey=AVTWFSWISMJXQV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50109322   

TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50109322([4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-(2-methyl-p...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against cAMP production in hGR-CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50109322([4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-(2-methyl-p...)
Affinity DataIC50: 7.00E+3nMAssay Description:Binding affinity of first diastereomer (D1) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50109322([4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-(2-methyl-p...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed