BDBM50109674 4'-Isoxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL149592

SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccno2)c1C

InChI Key InChIKey=YBRONYXWWAUIFR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109674   

TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109674(4'-Isoxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dim...)
Affinity DataKi:  270nMAssay Description:Binding affinity to CHO cells stably expressing human Endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109674(4'-Isoxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dim...)
Affinity DataKi:  3.90E+4nMAssay Description:Binding affinity to CHO cells stably expressing human Endothelin B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed