BDBM50109698 (S)-1-[(2S,4R)-2-Hydroxy-4-((R)-(R)-2-hydroxy-indan-1-ylcarbamoyl)-5-phenyl-pentyl]-4-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-ylmethyl)-piperazine-2-carboxylic acid tert-butylamide::CHEMBL356205

SMILES Cn1cc(CN2CCN(C[C@@H](O)C[C@@H](Cc3ccccc3)C(=O)NC3[C@H](O)Cc4ccccc34)[C@@H](C2)C(=O)NC(C)(C)C)ccc1=O

InChI Key InChIKey=ZKGUEBCOPNSUPC-SRRKGKDSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109698   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109698((S)-1-[(2S,4R)-2-Hydroxy-4-((R)-(R)-2-hydroxy-inda...)
Affinity DataIC50:  131nMAssay Description:In vitro inhibitory activity of the compound against mutant HIV-1 (A-44)proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109698((S)-1-[(2S,4R)-2-Hydroxy-4-((R)-(R)-2-hydroxy-inda...)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibitory activity of the compound against mutant HIV-1 (A-44)proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed