BDBM50109715 2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid amide::CHEMBL151128

SMILES CCc1cc(\C=C\S(N)(=O)=O)cc(c1)C(=O)c1ccccc1

InChI Key InChIKey=QLMJXRSFPIZIKN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50109715   

TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 1.20E+4nMAssay Description:Tested in vitro for inhibition of cyclooxygenase-2 in human blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested in vitro for inhibition of cyclooxygenase-1 in human blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed