BDBM50109933 2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-carboxylic acid 2-hydroxy-3-mercapto-1-mercaptomethyl-propyl ester::CHEMBL156166

SMILES OC(CS)C(CS)OC(=O)c1csc(n1)C1COc2ccccc2O1

InChI Key InChIKey=ULZTVJKTSYZRPI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50109933   

LigandPNGBDBM50109933(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109933(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  17nMAssay Description:Tested for the inhibition of Candida GGTase I in Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109933(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  17nMAssay Description:Tested for the inhibition of Candida GGTase I in Candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50109933(2-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-thiazole-4-c...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human geranylgeranyl transferase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed