BDBM50110234 CHEMBL9522::[8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-10-methyl-3,6,9,12,15-pentaoxo-1,2,4,7,10,13hexaaza-cyclopentadec-5-yl]-acetic acid

SMILES CC(C)C1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)C(CC(O)=O)NC(=O)NNC(=O)C(CCCNC(N)=N)NC1=O

InChI Key InChIKey=UYLKMCAJPYTSGJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50110234   

TargetIntegrin alpha-V/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110234([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-10-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110234([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-10-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110234([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-10-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50110234([8-Benzyl-14-(3-guanidino-propyl)-11-isopropyl-10-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed