BDBM50110431 CHEMBL3605776
SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(c2)C#Cc2cnc(NC3CCCCC3)nc2)cc(c1)C(F)(F)F
InChI Key InChIKey=JMMFXXPAQAEXJE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50110431
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 458nMAssay Description:Inhibition of Bcr-Abl T315I mutant (unknown origin) using Tyr2 peptide substrate after 2 hrs by FRET-based Z'-lyte assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of wild type Bcr-Abl (unknown origin) using Tyr2 peptide substrate after 2 hrs by FRET-based Z'-lyte assayMore data for this Ligand-Target Pair