BDBM50110447 CHEMBL352120::ethyl 5-{[1-(3-{4-[6-(2-chlorophenyl)-1,4-dimethyl-7,8,9,10-tetrahydro-4H-pyrido[4',3':4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-9-yl]butyl}phenyl)-1-(3-pyridyl)-(E)-methylideneamino]-oxy}-pentanoate

SMILES CCOC(=O)CCCCO\N=C(\c1cccnc1)c1cccc(CCCCN2CCc3c(C2)sc-2c3C(=NC(C)c3nnc(C)n-23)c2ccccc2Cl)c1

InChI Key InChIKey=PDCSYBRMRYSJDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110447   

TargetThromboxane-A synthase(Human)
Nikken Chemicals

Curated by ChEMBL
LigandPNGBDBM50110447(ethyl 5-{[1-(3-{4-[6-(2-chlorophenyl)-1,4-dimethyl...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of thromboxane synthase (TXA2) in human platelet microsomes [reduced formation of TXB2 from prostaglandin H2(PGH2)]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed