BDBM50110734 CHEMBL3605930

SMILES COc1ccc(Cl)cc1-c1c[nH]c2c(NS(C)(=O)=O)cccc12

InChI Key InChIKey=XCCRMYVOJIFMED-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50110734   

TargetGlucocorticoid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110734(CHEMBL3605930)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110734(CHEMBL3605930)
Affinity DataIC50: 143nMAssay Description:Antagonist activity against glucocorticoid receptor (unknown origin) expressed in HEK293 cells by GRE-dependent luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110734(CHEMBL3605930)
Affinity DataKi:  233nMAssay Description:Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110734(CHEMBL3605930)
Affinity DataKi:  697nMAssay Description:Displacement of [3H]-methyltrienolone from human androgen receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110734(CHEMBL3605930)
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity against glucocorticoid receptor in rat H4-IIE cells assessed as inhibition of dexamethasone-induced receptor transactivation pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110734(CHEMBL3605930)
Affinity DataKi:  4.47E+3nMAssay Description:Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed