BDBM50110811 CHEMBL3606010::US10800739, Compound (13)::US11420940, cpd (13)
SMILES NC(=O)c1cccc2CN(C3CCN(Cc4ccsc4)CC3)C(=O)c12
InChI Key InChIKey=RBNSMVGFGNNHLH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50110811
Affinity DataKd: <30nMAssay Description:Preferably, for the screening method above cited, both the PARP protein and the 5H-phenanthridin-6-one-derived probe of formula (IP) are pre-mixed, o...More data for this Ligand-Target Pair
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
Affinity DataKd: <30nMAssay Description:Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
Affinity DataKd: 3.70E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair