BDBM50110926 5-Methanesulfonyl-1-(4-methoxy-benzyl)-1H-indole-2-carboxylic acid methyl ester::CHEMBL31060

SMILES COC(=O)c1cc2cc(ccc2n1Cc1ccc(OC)cc1)S(C)(=O)=O

InChI Key InChIKey=LZXSTYYHVULMPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110926   

TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50110926(5-Methanesulfonyl-1-(4-methoxy-benzyl)-1H-indole-2...)
Affinity DataIC50: 780nMAssay Description:Inhibition of PGE-2 generation in LPS-stimulated human monocytes (Prostaglandin G/H synthase 2 cell assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50110926(5-Methanesulfonyl-1-(4-methoxy-benzyl)-1H-indole-2...)
Affinity DataIC50: 5.13E+4nMAssay Description:Inhibitory effect on Prostaglandin G/H synthase 2 activity was evaluated in human whole blood as LPS-induced PGE-2 generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed