BDBM50111123 (S)-1-((R)-2-Methanesulfonylamino-3,3-diphenyl-propionyl)-pyrrolidine-2-carboxylic acid (5-aminomethyl-thiophen-3-ylmethyl)-amide::CHEMBL8079

SMILES CS(=O)(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1csc(CN)c1

InChI Key InChIKey=JHORELGKNODOKT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111123   

TargetProthrombin(Human)
Life Science R & D, Lgci

Curated by ChEMBL
LigandPNGBDBM50111123((S)-1-((R)-2-Methanesulfonylamino-3,3-diphenyl-pro...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Life Science R & D, Lgci

Curated by ChEMBL
LigandPNGBDBM50111123((S)-1-((R)-2-Methanesulfonylamino-3,3-diphenyl-pro...)
Affinity DataKi:  606nMAssay Description:Binding affinity against bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Life Science R & D, Lgci

Curated by ChEMBL
LigandPNGBDBM50111123((S)-1-((R)-2-Methanesulfonylamino-3,3-diphenyl-pro...)
Affinity DataKi:  1.00E+5nMAssay Description:Compound was evaluated for the binding affinity against human Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed