BDBM50111691 13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5-oxo-(1R,6R,13S,15R,17R)-12,14,18-trioxapentacyclo[11.4.1.01,10.02,6.011,15]octadeca-3,8-dien-8-ylmethyl 2-(2-iodo-5-methoxy-4-methylcarbonyloxyphenyl)acetate::CHEMBL18058

SMILES C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)Cc1cc(OC)c(OC(C)=O)cc1I)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2

InChI Key InChIKey=ICTJNUKLXZURMF-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111691   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111691BDBM50111691(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]RTX binding to human Vanilloid receptor subtype 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111691BDBM50111691(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataEC50:  935nMAssay Description:Induced [Ca2+] influx in Vanilloid receptor subtype 1 expressing HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed