BDBM50111691 13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5-oxo-(1R,6R,13S,15R,17R)-12,14,18-trioxapentacyclo[11.4.1.01,10.02,6.011,15]octadeca-3,8-dien-8-ylmethyl 2-(2-iodo-5-methoxy-4-methylcarbonyloxyphenyl)acetate::CHEMBL18058

SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4O[C@]5(Cc6ccccc6)O[C@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)c(I)cc1OC(C)=O

InChI Key

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111691   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50111691(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]RTX binding to human Vanilloid receptor subtype 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50111691(13-benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5...)
Affinity DataEC50:  935nMAssay Description:Induced [Ca2+] influx in Vanilloid receptor subtype 1 expressing HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed