BDBM50111693 5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-ynyloxy-benzenesulfonyl)-amino]-benzamide::CHEMBL278060

SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OCC#C)cc1

InChI Key InChIKey=JMJKKHVSMQBPSU-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50111693   

LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 11nMAssay Description:Inhibition of porcine Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix metalloprotease-9 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Matrix metalloprotease-13 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 52nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 113nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 113nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111693(5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-yny...)
Affinity DataIC50: 113nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed