BDBM50111707 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-(1-methyl-piperidin-4-yl)-benzamide::CHEMBL278872

SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1c(cc(Br)cc1C(=O)NO)C1CCN(C)CC1

InChI Key InChIKey=ZLSOXSXSNCNKSX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50111707   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111707(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Matrix metalloprotease-9 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111707(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Matrix metalloprotease-13 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50111707(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50: 26nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111707(5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-m...)
Affinity DataIC50: 194nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed